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    <!-- http://purl.obolibrary.org/obo/CHEBI_24431 -->

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    <!-- http://purl.obolibrary.org/obo/CHEBI_44423 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_44423">
        <rdfs:label>hydroxyurea</rdfs:label>
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        <ns4:charge rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">0</ns4:charge>
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        <ns4:mass rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">76.055</ns4:mass>
        <oboInOwl:hasRelatedSynonym>carbamohydroxamic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>N-hydroxyurea</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Hydroxyharnstoff</oboInOwl:hasRelatedSynonym>
        <ns3:IAO_0000115>A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease.</ns3:IAO_0000115>
        <oboInOwl:hasDbXref>pdb-ccd:NHY</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>reaxys:1741548</oboInOwl:hasDbXref>
        <ns4:smiles_string>NC(=O)NO</ns4:smiles_string>
        <oboInOwl:hasDbXref>drugcentral:1399</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>carbamyl hydroxamate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:12107454</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>patent:US2705727</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>hmdb:HMDB0015140</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23318979</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>hydrea</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>hidroxicarbamida</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>N-carbamoylhydroxylamine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>beilstein:1741548</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:11391710</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>N-HYDROXYUREA</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:15772364</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>gmelin:130423</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>cas:127-07-1</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>hydroxycarbamide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>wikipedia.en:Hydroxyurea</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>hydroxycarbamidum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Hydroxyurea</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:11285159</oboInOwl:hasDbXref>
        <oboInOwl:id>CHEBI:44423</oboInOwl:id>
        <oboInOwl:hasRelatedSynonym>carbamohydroximic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>kegg.drug:D00341</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:44420</oboInOwl:hasAlternativeId>
        <oboInOwl:hasRelatedSynonym>hydroxyurea</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:11298103</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23643402</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:5816</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>metacyc.compound:HYDROXY-UREA</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Hydroxycarbamide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>kegg.compound:C07044</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:14988684</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>N-hydroxyurea</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Hydroxycarbamid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>oxyurea</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:11364534</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:11365149</oboInOwl:hasDbXref>
        <ns4:generalized_empirical_formula>CH4N2O2</ns4:generalized_empirical_formula>
        <oboInOwl:hasDbXref>pubmed:16356682</oboInOwl:hasDbXref>
        <ns4:inchi_key_string>VSNHCAURESNICA-UHFFFAOYSA-N</ns4:inchi_key_string>
        <ns4:inchi_string>InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)</ns4:inchi_string>
        <oboInOwl:hasDbXref>pubmed:22983419</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>N-HYDROXYUREA</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>carbamoyl oxime</oboInOwl:hasRelatedSynonym>
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        <oboInOwl:hasDbXref>pubmed:9271088</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23696560</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>drugbank:DB01005</oboInOwl:hasDbXref>
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