has_role organic heterocyclic compound zardaverine 0 268.06595 268.219 InChI=1S/C12H10F2N2O3/c1-18-10-6-7(2-4-9(10)19-12(13)14)8-3-5-11(17)16-15-8/h2-6,12H,1H3,(H,16,17) CiteXplore:8369979 6-[4-(difluoromethoxy)-3-methoxyphenyl]pyridazin-3(2H)-one CiteXplore:1723951 pubmed:8381357 CiteXplore:8381357 pubmed:7644776 pubmed:1723951 C12H10F2N2O3 zardaverinum chebi_ontology CiteXplore:1648920 CiteXplore:7684572 CiteXplore:1426207 CiteXplore:1787170 CiteXplore:12952271 cas:101975-10-4 CiteXplore:8392340 COc1cc(-c2ccc(=O)nn2)ccc1OC(F)F 6-[4-(difluoromethoxy)-3-methoxyphenyl]pyridazin-3(2H)-one CiteXplore:1700309 pubmed:1665311 pubmed:8369979 pubmed:7925141 pubmed:1700309 CiteXplore:8035322 CHEBI:46548 zardaverine 6-(4-DIFLUOROMETHOXY-3-METHOXY-PHENYL)-2H-PYRIDAZIN-3-ONE lincs.smallmolecule:LSM-2833 pubmed:8392340 zardaverina CiteXplore:1665311 CiteXplore:12387865 MESH:C066436 CiteXplore:7925141 pubmed:12387865 pubmed:1426207 pubmed:7684572 ChemIDplus:101975-10-4 6-(4-(Difluoromethoxy)-3-methoxyphenyl)-3(2H)-pyridazinone pubmed:1648920 HJMQDJPMQIHLPB-UHFFFAOYSA-N NCIt:C66686 CiteXplore:7644776 A pyridazinone derivative in which pyridazin-3(2<em>H</em>)-one is substituted at C-6 with a 4-(difluoromethoxy)-3-methoxyphenyl group. It is a phosphodiesterase inhibitor, selective for PDE3 and 4. pubmed:8035322 pubmed:12952271 pdb-ccd:ZAR pubmed:1787170 drug role