chemical entity ethambutol 0 204.18378 204.314 CC[C@@H](CO)NCCN[C@@H](CC)CO cas:74-55-5 pubmed:19648006 pubmed:17239593 CHEBI:678172 pubmed:12182855 (+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine S,S-Ethambutol reaxys:6312870 pubmed:17331717 EMB AEUTYOVWOVBAKS-UWVGGRQHSA-N (2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol pubmed:14695841 pubmed:19524332 etambutol pubmed:14698152 pubmed:10649975 (+)-S,S-ethambutol Ethambutol An ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (<i>S</i>,<i>S</i>-configuration). It is a bacteriostatic antimycobacterial drug, effective against <em>Mycobacterium tuberculosis</em> and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of <em>M. tuberculosis</em> are readily produced if ethambutol is used alone. chebi_ontology (+)-ethambutol drugbank:DB00330 drugcentral:1073 (2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol pubmed:16759086 pubmed:10966749 (+)-2,2'-(ethylenediimino)di-1-butanol pubmed:17276683 (2S,7S)-2,7-diethyl-3,6-diazaoctane-1,8-diol ethambutol (S,S)-ethambutol pubmed:16005211 pubmed:17851083 pubmed:17888665 pubmed:3934384 pubmed:16870429 pubmed:10891117 kegg.drug:D07925 CHEBI:659237 pubmed:17210775 C10H24N2O2 CHEBI:133410 ethambutolum wikipedia.en:Ethambutol pubmed:17315960 pubmed:15225698 InChI=1S/C10H24N2O2/c1-3-9(7-13)11-5-6-12-10(4-2)8-14/h9-14H,3-8H2,1-2H3/t9-,10-/m0/s1 CHEBI:4877 kegg.compound:C06984 pubmed:17562368