has_role organic heterocyclic compound antineoplastic agent protein kinase inhibitor gefitinib 0 446.1521 446.91 pubmed:27396387 pubmed:29493460 kegg.drug:D01977 chebi_ontology cas:184475-35-2 pubmed:30214852 pubmed:30069771 MESH:C419708 A member of the class of quinazolines that is quinazoline which is substituted by a (3-chloro-4-fluorophenyl)nitrilo group, 3-(morpholin-4-yl)propoxy group and a methoxy group at positions 4,6 and 7, respectively. An EGFR kinase inhibitor used for the treatment of non-small cell lung cancer. wikipedia.en:Gefitinib drugcentral:1282 N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine ZD1839 gefitinibum COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1 reaxys:8949523 pubmed:29332330 ZD-1839 pubmed:28968167 pubmed:20949670 InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27) NCIt:C1855 SNOMEDCT:398685009 drugbank:DB00317 N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine 4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline lincs.smallmolecule:LSM-1098 pubmed:29668619 SNOMEDCT:407100002 CHEBI:38917 hmdb:HMDB0014462 pubmed:15068398 gefitinib C22H24ClFN4O3 pubmed:30068310 ZD 1839 pubmed:29579334 pdb-ccd:IRE pubmed:20573926 pubmed:14981586 Irressat XGALLCVXEZPNRQ-UHFFFAOYSA-N Iressa CHEBI:49667 CHEBI:49668