has_role chemical entity antimicrobial agent antibacterial drug doxycycline 0 444.15327 444.44 metacyc.compound:CPD-19256 JBIWCJUYHHGXTC-AKNGSSGZSA-N pmc:PMC8464303 doxycycline chemspider:10469369 CHEBI:42135 InChI=1S/C22H24N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31)/t7-,10+,14+,15-,17-,22-/m0/s1 (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE drugcentral:961 Vibramycin CHEBI:4713 6alpha-deoxy-5-oxytetracycline patent:US3019260 Doxycyclin reaxys:3041790 pubmed:19630297 pubmed:34577552 NCIt:C457 Supracyclin knapsack:C00017127 hmdb:HMDB0014399 [H][C@@]12C(=C(O)[C@]3(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]3([H])[C@H]1O)C(=O)c1c(O)cccc1[C@@H]2C vsdb:1840 Doxycycline chebi_ontology doxycyclinum pubmed:34128838 pubmed:34551605 pubmed:1650428 5-hydroxy-alpha-6-deoxytetracycline pmc:PMC8466018 pubmed:16651635 pubmed:11891205 pdb-ccd:DXT pubmed:24134630 SNOMEDCT:372478003 CHEBI:50845 doxiciclina (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE C22H24N2O8 pubmed:23698443 pubmed:11850258 kegg.drug:D07876 drugbank:DB00254 pubmed:34355683 SNOMEDCT:10504007 pubmed:34338231 patent:US3200149 lipidmaps:LMPK07000001 wikipedia.en:Doxycycline (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide Jenacyclin doxycycline (anhydrous) Tetracycline in which the 5β-hydrogen is replaced by a hydroxy group, while the 6α-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis. pubmed:34318509 kegg.compound:C06973 MESH:D004318 pubmed:34228348 cas:564-25-0 pubmed:11477376