<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/EFO?iri=http://purl.obolibrary.org/obo/CHEBI_5118"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns5="https://w3id.org/chemrof/"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:obo="http://purl.obolibrary.org/obo#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/charge"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/mass"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/monoisotopic_mass"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/generalized_empirical_formula"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo#has_role -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo#has_role">
        <rdfs:label>has_role</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CHEBI_24431 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_24431">
        <rdfs:label>chemical entity</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35469 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35469">
        <rdfs:label>antidepressant</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_5118 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_5118">
        <rdfs:label>fluoxetine</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_24431"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo#has_role"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35469"/>
            </Restriction>
        </rdfs:subClassOf>
        <ns5:charge rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">0</ns5:charge>
        <ns5:monoisotopic_mass rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">309.13405</ns5:monoisotopic_mass>
        <ns5:mass rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">309.326</ns5:mass>
        <oboInOwl:hasDbXref>pubmed:24184049</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:24399719</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:8694321</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG DRUG:D00326 &quot;KEGG DRUG&quot;</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DrugBank:DB00472 &quot;DrugBank&quot;</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT:53640004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>wikipedia.en:Fluoxetine</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D005473</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG DRUG:54910-89-3 &quot;CAS Registry Number&quot;</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:22923967</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>rac-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>reaxys:3991406</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>(+-)-N-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Prozac</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:22903652</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>pubmed:25671301</oboInOwl:hasDbXref>
        <ns5:generalized_empirical_formula>C17H18F3NO</ns5:generalized_empirical_formula>
        <oboInOwl:hasRelatedSynonym>fluoxetinum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>ChemIDplus:54910-89-3 &quot;CAS Registry Number&quot;</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:24997906</oboInOwl:hasDbXref>
        <ns4:IAO_0000115>A racemate comprising equimolar amounts of (&lt;i&gt;R&lt;/i&gt;)- and (&lt;i&gt;S&lt;/i&gt;)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.</ns4:IAO_0000115>
        <oboInOwl:hasRelatedSynonym>rac-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:25448156</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>cas:54910-89-3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23885544</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:24464553</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>patent:DE2500110</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>fluoxetina</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:19144769</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>(+-)-N-methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>fluoxetine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Wikipedia:Fluoxetine &quot;Wikipedia&quot;</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>hmdb:HMDB0014615</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Patent:DE2500110 &quot;Patent&quot;</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>patent:US4314081</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:25639887</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT:372767007</oboInOwl:hasDbXref>
        <oboInOwl:id>CHEBI:5118</oboInOwl:id>
        <oboInOwl:hasDbXref>kegg.drug:D00326</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>beilstein:39914106</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Beilstein:39914106 &quot;Beilstein Registry Number&quot;</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>drugbank:DB00472</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Patent:US4314081 &quot;Patent&quot;</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIt:C506</oboInOwl:hasDbXref>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi/3_STAR"/>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



