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    <!-- http://purl.obolibrary.org/obo/CHEBI_15372 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_15372">
        <rdfs:label>5,6,7,8-tetrahydrobiopterin</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_59560 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_59560">
        <rdfs:label>sapropterin</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15372"/>
        <ns4:charge rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">0</ns4:charge>
        <ns4:monoisotopic_mass rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">241.11749</ns4:monoisotopic_mass>
        <ns4:mass rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">241.251</ns4:mass>
        <oboInOwl:hasRelatedSynonym>sapropterin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>6R-5,6,7,8-tetrahydrobiopterin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:23266371</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>tetrahydrobiopterin</oboInOwl:hasRelatedSynonym>
        <ns4:smiles_string>[H][C@]1([C@@H](O)[C@H](C)O)CNc2nc(N)nc(=O)c2N1</ns4:smiles_string>
        <oboInOwl:hasRelatedSynonym>sapropterina</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(6R)-L-erythro-tetrahydrobiopterin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>patent:EP191335</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>drugbank:DB00360</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-pteridinone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:1297822</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>metacyc.compound:CPD-14053</oboInOwl:hasDbXref>
        <oboInOwl:id>CHEBI:59560</oboInOwl:id>
        <oboInOwl:hasDbXref>pubmed:23712020</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>(-)-(6R)-2-amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(3H)-pteridinone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>hmdb:HMDB0000787</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>6R-L-5,6,7,8-tetrahydrobiopterin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>reaxys:4699705</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:21466737</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23690520</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>A tetrahydropterin that is 2-amino-5,6,7,8-tetrahydropteridin-4(3&lt;em&gt;H&lt;/em&gt;)-one in which a hydrogen at position 6 is substituted by a 1,2-dihydroxypropyl group (6&lt;i&gt;R&lt;/i&gt;,1&#39;&lt;i&gt;R&lt;/i&gt;,2&#39;&lt;i&gt;S&lt;/i&gt;-enantiomer).</ns3:IAO_0000115>
        <ns4:inchi_key_string>FNKQXYHWGSIFBK-RPDRRWSUSA-N</ns4:inchi_key_string>
        <oboInOwl:hasDbXref>pubmed:22575621</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23436109</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23462988</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:22110560</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:16510994</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>R-THBP</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>wikipedia.en:Sapropterin</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23705856</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:22112818</oboInOwl:hasDbXref>
        <ns4:generalized_empirical_formula>C9H15N5O3</ns4:generalized_empirical_formula>
        <oboInOwl:hasDbXref>kegg.drug:D08505</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:22388642</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>kegg.compound:C00272</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>5,6,7,8-Tetrahydrobiopterin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:22832064</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>6R-BH4</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pdb-ccd:H4B</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:22310224</oboInOwl:hasDbXref>
        <ns4:inchi_string>InChI=1S/C9H15N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17)/t3-,4+,6-/m0/s1</ns4:inchi_string>
        <oboInOwl:hasDbXref>pubmed:23743404</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:10333495</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23430527</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>(6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>cas:27070-47-9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23430545</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:21646032</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>knapsack:C00018229</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>cas:17528-72-2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:4004257</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>patent:US4713454</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:64242</oboInOwl:hasAlternativeId>
        <oboInOwl:hasRelatedSynonym>sapropterinum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:23235653</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>drugcentral:2612</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:19627172</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:22391997</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>(6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one</oboInOwl:hasRelatedSynonym>
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