chemical entity tenofovir (anhydrous) 0 287.07834 287.216 anhydrous tenofovir chebi_ontology (R)-PMPA A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection. SGOIRFVFHAKUTI-ZCFIWIBFSA-N C[C@H](Cn1cnc2c(N)ncnc21)OCP(=O)(O)O tenofovir pubmed:11777298 cas:147127-20-6 kegg.drug:D06074 reaxys:7415378 wikipedia.en:Tenofovir pubmed:28503983 pubmed:28166217 tenofovir (anh.) ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1 pubmed:25017682 hmdb:HMDB0014445 anh. tenofovir CHEBI:63625 drugbank:DB00300 lincs.smallmolecule:LSM-5340 ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid C9H14N5O4P