organic heterocyclic compound topiramate 0 339.09879 339.366 KJADKKWYZYXHBB-XBWDGYHZSA-N C12H21NO8S Topiramate pdb-ccd:TOR A hexose derivative that is 2,3:4,5-di-<em>O</em>-isopropylidene-β-<small>D</small>-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine. patent:US4513006 topiramato pubmed:22233396 drugcentral:2706 pubmed:22249827 topiramatum kegg.drug:D00537 topiramate InChI=1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9+,12+/m1/s1 RWJ-17021 2,3:4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate reaxys:5988957 chebi_ontology kegg.compound:C07502 wikipedia.en:Topiramate CC1(C)O[C@@H]2[C@@H](CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@@H]23)O1 tipiramate lincs.smallmolecule:LSM-5435 CHEBI:63631 tipiramato CHEBI:9633 McN-4853 Topamax drugbank:DB00273 TPM cas:97240-79-4 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate