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    <!-- http://purl.obolibrary.org/obo/CHEBI_26333 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_26333">
        <rdfs:label>prostaglandin</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_33575 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_33575">
        <rdfs:label>carboxylic acid</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_63925 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_63925">
        <rdfs:label>latanoprost free acid</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_26333"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33575"/>
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        <ns4:charge rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">0</ns4:charge>
        <ns4:monoisotopic_mass rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">390.24062</ns4:monoisotopic_mass>
        <ns4:mass rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">390.52</ns4:mass>
        <oboInOwl:hasRelatedSynonym>13,14-dihydro-17-phenyl-18,19,20-trinor-PGF2alpha</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:22124989</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ChEMBL:231987</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>(5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:21788077</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CiteXplore:21396362</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:22136089</oboInOwl:hasDbXref>
        <ns4:smiles_string>O=C(O)CCC/C=CC[C@@H]1[C@@H](CC[C@@H](O)CCc2ccccc2)[C@H](O)C[C@@H]1O</ns4:smiles_string>
        <oboInOwl:hasDbXref>CiteXplore:19289115</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:19084521</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:5911495</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Phxa 85</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>CiteXplore:22124989</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:18451496</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CiteXplore:20019365</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CiteXplore:19084521</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:C109345</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>(5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoic acid</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>cas:41639-83-2</oboInOwl:hasDbXref>
        <oboInOwl:id>CHEBI:63925</oboInOwl:id>
        <ns4:inchi_key_string>HNPFPERDNWXAGS-NFVOFSAMSA-N</ns4:inchi_key_string>
        <oboInOwl:hasDbXref>CiteXplore:22136089</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:20019365</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>A prostaglandin F&lt;small&gt;&lt;sub&gt;α&lt;/sub&gt;&lt;/small&gt; that is an analogue of prostaglandin F&lt;small&gt;&lt;sub&gt;2α&lt;/sub&gt;&lt;/small&gt; in which the pentyl group has been replaced by 2-phenylethyl and where the the 13,14-double bond has undergone formal hydrogenation. Its isopropyl ester prodrug, latanoprost, is used in the treatment of open-angle glaucoma and ocular hypertension.</ns3:IAO_0000115>
        <ns4:generalized_empirical_formula>C23H34O5</ns4:generalized_empirical_formula>
        <oboInOwl:hasDbXref>CiteXplore:18451496</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:21791206</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>latanoprost acid</oboInOwl:hasRelatedSynonym>
        <ns4:inchi_string>InChI=1S/C23H34O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,18-22,24-26H,2,7,10-16H2,(H,27,28)/b6-1-/t18-,19+,20+,21-,22+/m0/s1</ns4:inchi_string>
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        <oboInOwl:hasDbXref>pubmed:21396362</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ChemIDplus:41639-83-2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CiteXplore:21788077</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>reaxys:5911495</oboInOwl:hasDbXref>
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    <!-- http://www.ebi.ac.uk/efo/EFO_0004416 -->

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        <rdfs:label>acid</rdfs:label>
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