has_role drug chemical entity vasodilator agent nebivolol CiteXplore:18083889 Reaxys:4789059 pubmed:19443516 pubmed:18786089 pubmed:19815121 cas:118457-14-0 nebivolol CiteXplore:17661735 KEGG DRUG:D05127 (1RS,1'RS)-2,2'-iminobis{1-[(2RS,2'SR)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol} pubmed:18078016 pubmed:18221115 drugbank:DB04861 A racemate consisting of equal amounts of (<i>R</i>,<i>S</i>,<i>S</i>,<i>S</i>)-nebivolol and (<i>S</i>,<i>R</i>,<i>R</i>,<i>R</i>)-nebivolol. A cardioselective beta blocker, it has vasodilatory activity but lacks intrinsic sympathomimetic and membrane-stabilising activity. It is used as the hydrochloride salt for the management of hypertension, and as an adjunct to standard therapy in elderly patients with stable chronic heart failure. chebi_ontology pubmed:23314750 kegg.drug:D05127 CiteXplore:19443516 (1RS,1'RS)-1,1'-[(2RS,2'SR)-bis(6-fluorochroman-2-yl)]-2,2'-iminodiethanol dl-nebivolol SNOMEDCT:318638009 CiteXplore:18786089 pubmed:18083889 nebivololum wikipedia.en:Nebivolol SNOMEDCT:395808005 CiteXplore:18078016 CiteXplore:18221115 CiteXplore:20620250 ChemIDplus:118457-14-0 patent:US4654362 reaxys:4789059 CiteXplore:19815121 pubmed:17661735 NCIt:C66221 CHEBI:64022 MESH:C052753 pubmed:20620250