has_role organic heterocyclic compound serotonergic drug N-desmethylclozapine 0 312.11417 312.804 pubmed:21855612 SNOMEDCT:115561003 chebi_ontology CHEBI:64050 CiteXplore:21835172 pubmed:21658379 MESH:C058272 cas:6104-71-8 Reaxys:762289 pubmed:20156258 N-desmethyl clozapine CiteXplore:20156258 Demethylclozapine ChemIDplus:6104-71-8 8-chloro-11-(piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine Clc1ccc2c(c1)N=C(N1CCNCC1)c1ccccc1N2 CiteXplore:21658379 NDMC CiteXplore:21917240 InChI=1S/C17H17ClN4/c18-12-5-6-15-16(11-12)21-17(22-9-7-19-8-10-22)13-3-1-2-4-14(13)20-15/h1-6,11,19-20H,7-10H2 pubmed:21712711 MESH:C411706 Norclozapine C17H17ClN4 pubmed:21134422 pubmed:20463634 pubmed:21726287 JNNOSTQEZICQQP-UHFFFAOYSA-N CiteXplore:21912901 CiteXplore:20463634 wikipedia.en:Desmethylclozapine 8-Chloro-11-(1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine pubmed:21835172 8-chloro-11-(piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine CiteXplore:21855612 A dibenzodoazepine substituted with chloro and piperazino groups which is a major metabolite of clozapine; a potent and selective 5-HT2C serotonin receptor antagonist. reaxys:762289 pubmed:21912901 Desmethylclozapine CiteXplore:21712711 pubmed:21917240 CiteXplore:21134422 CiteXplore:21726287 ChEMBL:162934