has_role dopamine agonist (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride 0 365.17577 365.901 (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydro-1H-isochromene-5,6-diol hydrochloride ChemIDplus:145307-34-2 reaxys:5859104 (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydro-1H-isochromene-5,6-diol hydrochloride A hydrochloride salt obtained by mixing equimolar amounts of (1<i>R</i>,3<i>S</i>)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol with hydrochloric acid. Potent and selective dopamine D<small>₁</small>-like receptor agonist (pEC50 values are 8.97 and < 5 for D<small>₁</small>-like and D<small>₂</small>-like receptors respectively). Displays anti-Parkinsonian activity following oral administration in vivo. A77636 hydrochloride Reaxys:5859104 chebi_ontology A 77636 InChI=1S/C20H27NO3.ClH/c21-10-17-14-1-2-16(22)19(23)15(14)6-18(24-17)20-7-11-3-12(8-20)5-13(4-11)9-20;/h1-2,11-13,17-18,22-23H,3-10,21H2;1H/t11?,12?,13?,17-,18-,20?;/m0./s1 C20H27NO3.HCl [(1R,3S)-3-(adamantan-1-yl)-5,6-dihydroxy-3,4-dihydro-1H-isochromen-1-yl]methanaminium chloride cas:145307-34-2 ChEMBL:805869 BWHPNJVKFAPVOG-QYFJGNGUSA-N MESH:C079415 CHEBI:64078 A 77636 hydrochloride 3-(1'-Adamantyl)-1-aminomethyl-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyran hydrochloride A-77636 Cl.NC[C@@H]1O[C@H](C23CC4CC(CC(C4)C2)C3)Cc2c1ccc(O)c2O A77636 ionic salt