chemical entity sodium 8-bromo-3',5'-cyclic GMP 0 444.93989 446.086 8-bromoguanosine 3',5'-cyclic phosphate sodium salt reaxys:8378760 CHEBI:64104 sodium 8-bromoguanosine 3',5'-phosphate ZJRFCXHKYQVNFK-YEOHUATISA-M 8-bromoguanosine 3',5'-cyclic phosphate sodium Nc1nc(=O)c2nc(Br)n([C@@H]3O[C@@H]4COP(=O)([O-])O[C@H]4[C@H]3O)c2n1.[Na+] chebi_ontology 8-bromo cGMP sodium salt InChI=1S/C10H11BrN5O7P.Na/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(22-8)1-21-24(19,20)23-5;/h2,4-5,8,17H,1H2,(H,19,20)(H3,12,14,15,18);/q;+1/p-1/t2-,4-,5-,8-;/m1./s1 sodium 8-bromoguanosine 3',5'-cyclic phosphate sodium 8-bromoguanosine 3',5'-phosphate C10H10BrN5O7P.Na An organic sodium salt having 8-bromoguanosine 3',5'-cyclic phosphate as the counterion. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1α and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro.