chemical entity depudecin 0 212.10486 212.245 reaxys:6803701 A polyketide obtained from the fungus <em>Alternaria brassicicola</em> and having a highly unusual structure of an 11-carbon chain containing two epoxides and six stereogenic centres. It is an inhibitor of histone deacetylase (HDAC) both <em>in vivo</em> and <em>in vitro</em> and also exhibits anti-angiogenic activity. C11H16O4 (1S,3E,6S)-1,2:5,6-dianhydro-3,4-dideoxy-1-[(1R)-1-hydroxyethyl]-6-[(1R)-1-hydroxyprop-2-en-1-yl]-D-threo-hex-3-enitol pubmed:10737176 cas:139508-73-9 pubmed:9520362 pubmed:19737099 (1R)-1-{(2S,3S)-3-[(E)-2-{(2S,3S)-3-[(1R)-1-hydroxyethyl]oxiran-2-yl}ethenyl]oxiran-2-yl}prop-2-en-1-ol pubmed:8845831 4,5:8,9-dianhydro-1,2,6,7,11-pentadeoxy-D-threo-D-ido-undeca-1,6-dienitol (-)-depudecin pubmed:9520369 InChI=1S/C11H16O4/c1-3-7(13)11-9(15-11)5-4-8-10(14-8)6(2)12/h3-13H,1H2,2H3/b5-4+/t6-,7-,8+,9+,10+,11+/m1/s1 CHEBI:64143 pubmed:9383455 pubmed:12623206 (1S,3E,6S)-1,2:5,6-dianhydro-3,4-dideoxy-1-[(1R)-1-hydroxyethyl]-6-[(1R)-1-hydroxyprop-2-en-1-yl]-D-threo-hex-3-enitol pubmed:11562279 chebi_ontology pubmed:1731795 (1R)-1-{(2S,3S)-3-[(E)-2-{(2S,3S)-3-[(1R)-1-hydroxyethyl]oxiran-2-yl}ethenyl]oxiran-2-yl}prop-2-en-1-ol DLVJMFOLJOOWFS-INMLLLKOSA-N [H][C@@]1([C@H](O)C=C)O[C@H]1/C=C/[C@@H]1O[C@@]1([H])[C@@H](C)O pubmed:1500354