has_role phenols benserazide 0 257.10117 257.246 CiteXplore:22236652 pubmed:12703659 BNQDCRGUHNALGH-UHFFFAOYSA-N kegg.drug:D03082 A carbohydrazide that results from the formal condensation of the carboxy group of <small>D</small><small>L</small>-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-<small>L</small>-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone. wikipedia.en:Benserazide NC(CO)C(=O)NNCc1ccc(O)c(O)c1O patent:BE619015 reaxys:3984490 cas:322-35-0 Ro 44602 benserazida 2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide Reaxys:3984490 ChemIDplus:322-35-0 C10H15N3O5 benserazide Ro 4-4602 CHEBI:64187 SNOMEDCT:391821005 CiteXplore:12703659 pubmed:22236652 KEGG DRUG:D03082 DL-serine 2-(2,3,4-trihydroxybenzyl)hydrazide benserazidum InChI=1S/C10H15N3O5/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16/h1-2,6,12,14-17H,3-4,11H2,(H,13,18) chebi_ontology lincs.smallmolecule:LSM-5097 drugcentral:314 patent:US3178476 NCIt:C81109 2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide MESH:D001545 SNOMEDCT:420240007 DL-serine 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide ChEMBL:727070 drug role