has_role organic heterocyclic compound carboxamide nafadotride 0 365.21033 365.477 N-[(1-butylpyrrolidin-2-yl)methyl]-4-cyano-1-methoxynaphthalene-2-carboxamide A naphthalenecarboxamide resulting from the formal condensation of the carboxylic acid group of 4-cyano-1-methoxynaphthalene-2-carboxylic acid with the primary amino group of 1-(1-butylpyrrolidin-2-yl]methanamine. It is a highly potent, competitive, preferential dopamine D<small>₃</small> receptor antagonist, centrally active upon systemic administration. ChEMBL:134432 Reaxys:8356954 MESH:C097285 wikipedia.en:Nafadotride CiteXplore:9252981 CHEBI:64191 C22H27N3O2 pubmed:9252981 cas:149649-22-9 nafadotride CiteXplore:8531087 IDZASIQMRGPBCQ-UHFFFAOYSA-N InChI=1S/C22H27N3O2/c1-3-4-11-25-12-7-8-17(25)15-24-22(26)20-13-16(14-23)18-9-5-6-10-19(18)21(20)27-2/h5-6,9-10,13,17H,3-4,7-8,11-12,15H2,1-2H3,(H,24,26) reaxys:8356954 N-[(1-butylpyrrolidin-2-yl)methyl]-4-cyano-1-methoxynaphthalene-2-carboxamide ChemIDplus:149649-22-9 lincs.smallmolecule:LSM-1755 pubmed:8531087 CCCCN1CCCC1CNC(=O)c1cc(C#N)c2ccccc2c1OC chebi_ontology (+-)-nafadotride drug role