has_role
chemical entity
serotonergic drug
serotonergic antagonist
dopamine agonist
metergoline
0
403.22598
403.526
C25H29N3O2
pubmed:20377624
NIST Chemistry WebBook:17692-51-2
pubmed:19509219
drugcentral:1723
reaxys:5362415
CiteXplore:21354537
lincs.smallmolecule:LSM-3265
kegg.drug:D07218
CiteXplore:19945477
pubmed:19538518
Metergolin
CiteXplore:21600959
ChEMBL:121938
pubmed:18996971
benzyl {[(8alpha)-1,6-dimethylergolin-8-yl]methyl}carbamate
Reaxys:5362415
1-Methyl-N-carbobenzyloxydihydro-D-lysergamin
KEGG DRUG:D07218
benzyl {[(8alpha)-1,6-dimethylergolin-8-yl]methyl}carbamate
(((8-beta)-1,6-Dimethylergolin-8-yl)methyl)carbamic acid benzyl ester
An ergoline alkaloid that is the <em>N</em>-benzyloxycarbonyl derivative of lysergamine. A 5-HT<small><sub>2</sub></small> antagonist. Also 5-HT<small><sub>1</sub></small> antagonist and 5-HT<small><sub>1D</sub></small> ligand. Has moderate affinity for 5-HT<small><sub>6</sub></small> and high affinity for 5-HT<small><sub>7</sub></small>.
WZHJKEUHNJHDLS-QTGUNEKASA-N
CiteXplore:19539656
CHEBI:64216
CiteXplore:22218419
CiteXplore:20451398
CiteXplore:21880033
CiteXplore:19632276
metergolina
MESH:D008711
pubmed:21475142
1,6-Dimethyl-8-beta-carbobenzyloxaminomethyl-10-alpha-ergoline
CiteXplore:19484723
pubmed:21600959
pubmed:24134630
ChemIDplus:17692-51-2
CiteXplore:18996971
CiteXplore:20845263
pubmed:21354537
InChI=1S/C25H29N3O2/c1-27-14-18(13-26-25(29)30-16-17-7-4-3-5-8-17)11-21-20-9-6-10-22-24(20)19(12-23(21)27)15-28(22)2/h3-10,15,18,21,23H,11-14,16H2,1-2H3,(H,26,29)/t18-,21+,23+/m0/s1
1-Methyl-8-beta-carbobenzyloxyaminomethyl-10-alpha-ergoline
(+)-N-(Carboxy)-1-methyl-9,10-dihydrolysergamine benzyl ester
metergolinum
CiteXplore:21475142
pubmed:20845263
CiteXplore:20377624
pubmed:19484723
CiteXplore:19538518
CiteXplore:19509219
[H][C@@]12Cc3cn(C)c4cccc(c34)[C@@]1([H])C[C@@H](CNC(=O)OCc1ccccc1)CN2C
pubmed:19945477
pubmed:21880033
(((8-beta)-1,6-Dimethylergolin-8-yl)methyl)carbamic acid phenylmethyl ester
wikipedia.en:Metergoline
D-8-beta-((Carboxyamino)methyl)-1,6-dimethylergoline benzyl ester
cas:17692-51-2
D-8-beta-((Carbobenzoxyamino)methyl)-1,6-dimethyl-10-alpha-ergoline
pubmed:20451398
pubmed:19632276
chebi_ontology
NCIt:C91039
KEGG DRUG:17692-51-2
pubmed:22218419
metergoline
pubmed:19539656