organic heterocyclic compound dabrafenib 0 519.10105 519.574 pubmed:23807941 pubmed:23608920 cas:1195765-45-7 CHEBI:75045 BFSMGDJOXZAERB-UHFFFAOYSA-N patent:WO2011047238 pubmed:23617957 pubmed:23463215 pubmed:23552670 pubmed:23833299 N-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide pubmed:22981500 pubmed:23709751 pubmed:23290787 wikipedia.en:Dabrafenib pubmed:23537694 pubmed:23470635 drugcentral:4801 pubmed:23276366 pubmed:23317446 pubmed:23249624 InChI=1S/C23H20F3N5O2S2/c1-23(2,3)21-30-18(19(34-21)16-10-11-28-22(27)29-16)12-6-4-9-15(17(12)26)31-35(32,33)20-13(24)7-5-8-14(20)25/h4-11,31H,1-3H3,(H2,27,28,29) pubmed:23881668 pubmed:23844038 dabrafenib pubmed:23795808 pubmed:23846776 reaxys:19689971 C23H20F3N5O2S2 pubmed:23403819 chebi_ontology kegg.drug:D10064 pubmed:23656699 lincs.smallmolecule:LSM-6303 pubmed:23714462 pubmed:23870055 pubmed:23515890 N-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide CC(C)(C)c1nc(-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2F)c(-c2ccnc(N)n2)s1 An organofluorine compound and antineoplastic agent, used as its mesylate salt in treatment of metastatic melanoma. pubmed:23237741 pubmed:23621583