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    <!-- http://purl.obolibrary.org/obo/CHEBI_16670 -->

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        <rdfs:label>peptide</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_75431 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_75431">
        <rdfs:label>ghrelin</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16670"/>
        <ns4:charge rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">0</ns4:charge>
        <ns4:monoisotopic_mass rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">3368.87933</ns4:monoisotopic_mass>
        <ns4:mass rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">3370.918</ns4:mass>
        <oboInOwl:hasDbXref>pubmed:23307791</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:28538835</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>wikipedia.en:Ghrelin</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>lenomorelin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:23178701</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23317782</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:28542403</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>H-Gly-Ser-Ser(n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg-OH</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:23982275</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23704134</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>glycyl-L-seryl-O-octanoyl-L-seryl-L-phenylalanyl-L-leucyl-L-seryl-L-prolyl-L-alpha-glutamyl-L-histidyl-L-glutaminyl-L-arginyl-L-valyl-L-glutaminyl-L-glutaminyl-L-arginyl-L-lysyl-L-alpha-glutamyl-L-seryl-L-lysyl-L-lysyl-L-prolyl-L-prolyl-L-alanyl-L-lysyl-L-leucyl-L-glutaminyl-L-prolyl-L-arginine</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>pubmed:23159561</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23359315</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:15788704</oboInOwl:hasDbXref>
        <ns4:inchi_string>InChI=1S/C149H249N47O42/c1-9-10-11-12-16-45-118(209)238-78-106(191-135(225)103(75-197)171-115(204)73-154)137(227)187-101(71-84-32-14-13-15-33-84)133(223)186-100(70-81(4)5)132(222)190-105(77-199)144(234)194-66-29-42-108(194)139(229)180-95(51-57-117(207)208)128(218)188-102(72-85-74-165-79-169-85)134(224)179-92(47-53-112(156)201)126(216)175-90(39-26-63-167-148(161)162)130(220)192-119(82(6)7)141(231)181-93(48-54-113(157)202)127(217)177-91(46-52-111(155)200)125(215)174-89(38-25-62-166-147(159)160)122(212)173-87(35-18-22-59-151)121(211)178-94(50-56-116(205)206)129(219)189-104(76-198)136(226)176-88(36-19-23-60-152)123(213)182-96(37-20-24-61-153)142(232)196-68-31-44-110(196)145(235)195-67-30-41-107(195)138(228)170-83(8)120(210)172-86(34-17-21-58-150)124(214)185-99(69-80(2)3)131(221)183-97(49-55-114(158)203)143(233)193-65-28-43-109(193)140(230)184-98(146(236)237)40-27-64-168-149(163)164/h13-15,32-33,74,79-83,86-110,119,197-199H,9-12,16-31,34-73,75-78,150-154H2,1-8H3,(H2,155,200)(H2,156,201)(H2,157,202)(H2,158,203)(H,165,169)(H,170,228)(H,171,204)(H,172,210)(H,173,212)(H,174,215)(H,175,216)(H,176,226)(H,177,217)(H,178,211)(H,179,224)(H,180,229)(H,181,231)(H,182,213)(H,183,221)(H,184,230)(H,185,214)(H,186,223)(H,187,227)(H,188,218)(H,189,219)(H,190,222)(H,191,225)(H,192,220)(H,205,206)(H,207,208)(H,236,237)(H4,159,160,166)(H4,161,162,167)(H4,163,164,168)/t83-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,119-/m0/s1</ns4:inchi_string>
        <oboInOwl:hasDbXref>pubmed:23278489</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>lenomorelinum</oboInOwl:hasRelatedSynonym>
        <ns4:smiles_string>CCCCCCCC(=O)OC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cncn1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C</ns4:smiles_string>
        <oboInOwl:hasDbXref>pubmed:28621678</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>kegg.compound:C16025</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23316086</oboInOwl:hasDbXref>
        <ns4:inchi_key_string>GNKDKYIHGQKHHM-RJKLHVOGSA-N</ns4:inchi_key_string>
        <oboInOwl:hasDbXref>pubmed:23652399</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Ghrelin (human)</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:23965296</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>GSS(octanoyl)FLSPEHQRVQQRKESKKPPAKLQPR</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:23804489</oboInOwl:hasDbXref>
        <oboInOwl:id>CHEBI:75431</oboInOwl:id>
        <oboInOwl:hasDbXref>pubmed:23698230</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23989358</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>GS-S(n-octanoyl)-FLSPEHQRVQQRKESKKPPAKLQPR</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>lenomorelina</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Human ghrelin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Gastric MLTRP</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:23481295</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23624808</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23843943</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23652386</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>cas:304853-26-7</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23652420</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Motilin-related peptide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>reaxys:24715767</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23778458</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23847595</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>cas:258279-04-8</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>glycyl-L-seryl-O-octanoyl-L-seryl-L-phenylalanyl-L-leucyl-L-seryl-L-prolyl-L-alpha-glutamyl-L-histidyl-L-glutaminyl-L-arginyl-L-valyl-L-glutaminyl-L-glutaminyl-L-arginyl-L-lysyl-L-alpha-glutamyl-L-seryl-L-lysyl-L-lysyl-L-prolyl-L-prolyl-L-alanyl-L-lysyl-L-leucyl-L-glutaminyl-L-prolyl-L-arginine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:23631903</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:28704966</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23808302</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23428971</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>lenomoreline</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:28547758</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>A 28-membered appetite-stimulating polypeptide consisting of Gly, Ser, Ser(octanoyl), Phe, Leu, Ser, Pro, Glu, His, Gln, Arg, Val, Gln, Gln, Arg, Lys, Glu, Ser, Lys, Lys, Pro, Pro, Ala, Lys, Leu, Gln, Pro and Arg residues joined in sequence. The &lt;em&gt;O&lt;/em&gt;-&lt;em&gt;n&lt;/em&gt;-octanoylation of the side-chain hydroxy group of serine-3 (Ser3) is essential for ghrelin&#39;s activity.</ns3:IAO_0000115>
        <oboInOwl:hasDbXref>pubmed:28590260</oboInOwl:hasDbXref>
        <ns4:generalized_empirical_formula>C149H249N47O42</ns4:generalized_empirical_formula>
        <oboInOwl:hasDbXref>pubmed:23524619</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Gly-Ser-Ser(octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg</oboInOwl:hasRelatedSynonym>
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