chemical entity sertraline 0 305.0738 306.236 chebi_ontology sertralinum pubmed:19502000 kegg.compound:C07246 [H][C@@]1(c2ccc(Cl)c(Cl)c2)CC[C@H](NC)c2ccccc21 cas:79617-96-2 kegg.drug:D02360 CP 51974 reaxys:5753709 drugcentral:2436 (1S,4S)-sertraline (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine hmdb:HMDB0005010 sertraline pdb-ccd:SRE VGKDLMBJGBXTGI-SJCJKPOMSA-N C17H17Cl2N pubmed:21823671 drugbank:DB01104 (+)-sertraline Sertraline A member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the <i>S</i>,<i>S</i> diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder. sertralina InChI=1S/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17-/m0/s1 (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine lincs.smallmolecule:LSM-3843 (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine cis-(+)-sertraline wikipedia.en:Sertraline patent:US4536518 CHEBI:9123