has_role carboxylic acid non-steroidal anti-inflammatory drug EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor sulindac 0 356.08824 356.418 sulindac drugbank:DB00605 {(1Z)-5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl}acetic acid Sulindac CHEBI:9352 cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid A monocarboxylic acid that is 1-benzylidene-1<em>H</em>-indene which is substituted at positions 2, 3, and 5 by methyl, carboxymethyl, and fluorine respectively, and in which the phenyl group of the benzylidene moiety is substituted at the <em>para</em> position by a methylsulfinyl group. It is a prodrug for the corresponding sulfide, a non-steroidal anti-inflammatory drug, used particularly in the treatment of acute and chronic inflammatory conditions. wikipedia.en:Sulindac C20H17FO3S pdb-ccd:SUZ patent:US3654349 pubmed:15123337 reaxys:2951842 drugcentral:2534 Sulindacum kegg.drug:D00120 SNOMEDCT:387513000 kegg.compound:C01531 (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid MESH:D013467 chebi_ontology hmdb:HMDB0014743 cas:38194-50-2 cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid {(1Z)-5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl}acetic acid pubmed:11569947 pubmed:11927004 pubmed:23689354 pubmed:12406542 pubmed:19884509 pubmed:15020200 patent:DE2039426 InChI=1S/C20H17FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9- Clinoril sulindaco pubmed:23804703 MLKXDPUZXIRXEP-MFOYZWKCSA-N SNOMEDCT:89505005 NCIt:C850 CC1=C(CC(=O)O)c2cc(F)ccc2/C1=Cc1ccc(S(C)=O)cc1