<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/EFO?iri=http://purl.obolibrary.org/obo/CHEBI_9467"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:obo="http://purl.obolibrary.org/obo#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo#has_role -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo#has_role">
        <rdfs:label>has_role</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CHEBI_24431 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_24431">
        <rdfs:label>chemical entity</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35476 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35476">
        <rdfs:label>antipsychotic agent</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35640 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35640">
        <rdfs:label>adrenergic uptake inhibitor</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_9467 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_9467">
        <rdfs:label>tetrabenazine</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_24431"/>
        <rdfs:subClassOf>
            <Class>
                <intersectionOf rdf:parseType="Collection">
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo#has_role"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35476"/>
                    </Restriction>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo#has_role"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35640"/>
                    </Restriction>
                </intersectionOf>
            </Class>
        </rdfs:subClassOf>
        <oboInOwl:hasDbXref>reaxys:9356999</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Nitoman</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>patent:US2830993</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG DRUG:D08575</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>tetrabenazinum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>ChemIDplus:58-46-8</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:21487088</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CiteXplore:10686169</oboInOwl:hasDbXref>
        <oboInOwl:id>CHEBI:9467</oboInOwl:id>
        <oboInOwl:hasDbXref>Reaxys:9356999</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:20442355</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>KEGG COMPOUND:58-46-8</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CiteXplore:19929707</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:20869622</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>tetrabenazine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>rac-(3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>tetrabenazina</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>TBZ</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>CiteXplore:20442355</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG COMPOUND:C11168</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Ro 1-9569</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>cas:58-46-8</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CiteXplore:20869622</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>2-oxo-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzoquinolizine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>CiteXplore:9040721</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo(a)quinolizin-2-one</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:9040721</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT:363581004</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>rac-(3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>NCIt:C81095</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>kegg.compound:C11168</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>wikipedia.en:Tetrabenazine</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:19929707</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:10686169</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D013747</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>drugbank:DB04844</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>kegg.drug:D08575</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Tetrabenazine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>CiteXplore:21487088</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Xenazine</oboInOwl:hasRelatedSynonym>
        <ns4:IAO_0000115>A racemate consisting of equal amounts of (3&lt;i&gt;R&lt;/i&gt;,11b&lt;i&gt;R&lt;/i&gt;)- and (3&lt;i&gt;S&lt;/i&gt;,11b&lt;i&gt;S&lt;/i&gt;)-9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2&lt;em&gt;H&lt;/em&gt;-pyrido[2,1-&lt;em&gt;a&lt;/em&gt;]isoquinolin-2-one. An adrenergic uptake inhibitor, it was formerly used as an antipsychotic, but it is now used mainly for the treatment of various movement disorders including chorea, ballism, dystonias, and tardive dyskinesia.</ns4:IAO_0000115>
        <oboInOwl:hasDbXref>NIST Chemistry WebBook:58-46-8</oboInOwl:hasDbXref>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi/3_STAR"/>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



