chemical entity tramadol 0 263.18853 263.375 U-26225A pubmed:25219922 pubmed:23962470 pubmed:23098678 pubmed:23543914 patent:GB997399 E-265 pubmed:23668411 (+-)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol pubmed:23907474 pubmed:22674657 CG-315E pubmed:24014188 tramadolum pubmed:23292128 pubmed:23822079 pubmed:23031839 pubmed:23145962 pubmed:23840975 tramadol pubmed:23102445 pubmed:22943675 pubmed:23328338 drugbank:DB00193 rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol pubmed:23433451 pubmed:23099620 pubmed:22964800 CHEBI:9648 C16H25NO2 A racemate consisting of equal amounts of (<i>R</i>,<i>R</i>)- and (<i>S</i>,<i>S</i>)-tramadol. A centrally acting synthetic opioid analgesic, used (as the hydrochloride salt) to treat moderately severe pain. The (<i>R</i>,<i>R</i>)-enantiomer exhibits ten-fold higher analgesic potency than the (<i>S</i>,<i>S</i>)-enantiomer. Originally developed by Grünenthal GmbH and launched in 1977, it was subsequently isolated from the root bark of the South African tree <em>Nauclea latifolia</em>. chebi_ontology hmdb:HMDB0014339 reaxys:2943832 wikipedia.en:Tramadol rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol pubmed:23061925 patent:US3652589 pubmed:23872384 pubmed:23755929 pubmed:23095734 kegg.compound:C07153 kegg.drug:D08623 pubmed:23773348 cas:27203-92-5 pubmed:23756535 pubmed:23843224 pubmed:23825758