<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/EFO?iri=http://purl.obolibrary.org/obo/CHEBI_9753"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:obo2="http://purl.obolibrary.org/obo#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:obo="http://purl.obolibrary.org/obo/"
     xmlns:ns4="https://w3id.org/chemrof/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="https://w3id.org/chemrof/inchi_key_string"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/smiles_string"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/charge"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/generalized_empirical_formula"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/mass"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/inchi_string"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/monoisotopic_mass"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo#has_role -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo#has_role">
        <rdfs:label>has_role</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CHEBI_22586 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_22586">
        <rdfs:label>antioxidant</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_24532 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_24532">
        <rdfs:label>organic heterocyclic compound</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35526 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35526">
        <rdfs:label>hypoglycemic agent</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35620 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35620">
        <rdfs:label>vasodilator agent</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35623 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35623">
        <rdfs:label>anticonvulsant</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_9753 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_9753">
        <rdfs:label>troglitazone</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_24532"/>
        <rdfs:subClassOf>
            <Class>
                <unionOf rdf:parseType="Collection">
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo#has_role"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_22586"/>
                    </Restriction>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo#has_role"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35526"/>
                    </Restriction>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo#has_role"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35620"/>
                    </Restriction>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo#has_role"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35623"/>
                    </Restriction>
                </unionOf>
            </Class>
        </rdfs:subClassOf>
        <ns4:charge rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">0</ns4:charge>
        <ns4:monoisotopic_mass rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">441.16099</ns4:monoisotopic_mass>
        <ns4:mass rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">441.549</ns4:mass>
        <oboInOwl:hasDbXref>wikipedia.en:Troglitazone</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>troglitazone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>kegg.drug:D00395</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT:109085002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>cas:97322-87-7</oboInOwl:hasDbXref>
        <ns4:smiles_string>Cc1c(C)c2c(c(C)c1O)CCC(C)(COc1ccc(CC3SC(=O)NC3=O)cc1)O2</ns4:smiles_string>
        <oboInOwl:hasRelatedSynonym>5-(4-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2,4-dione</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>5-{4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methoxy]benzyl}-1,3-thiazolidine-2,4-dione</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Romglizone</oboInOwl:hasRelatedSynonym>
        <ns4:generalized_empirical_formula>C24H27NO5S</ns4:generalized_empirical_formula>
        <ns4:inchi_key_string>GXPHKUHSUJUWKP-UHFFFAOYSA-N</ns4:inchi_key_string>
        <oboInOwl:hasDbXref>SNOMEDCT:386967007</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Troglitazone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>drugcentral:2767</oboInOwl:hasDbXref>
        <oboInOwl:id>CHEBI:9753</oboInOwl:id>
        <oboInOwl:hasRelatedSynonym>Rezulin (TN)</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>drugbank:DB00197</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>metacyc.compound:CPD-11439</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:C057693</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>beilstein:4338399</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>(+-)-all-rac-5-(p-((6-Hydroxy-2,5,7,8-tetramethyl-2-chromanyl)methoxy)benzyl)-2,4-thiazolidinedione</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>NCIt:C1522</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>troglitazonum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>patent:US4572912</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>lincs.smallmolecule:LSM-4890</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>5-{4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methoxy]benzyl}-1,3-thiazolidine-2,4-dione</oboInOwl:hasExactSynonym>
        <ns4:inchi_string>InChI=1S/C24H27NO5S/c1-13-14(2)21-18(15(3)20(13)26)9-10-24(4,30-21)12-29-17-7-5-16(6-8-17)11-19-22(27)25-23(28)31-19/h5-8,19,26H,9-12H2,1-4H3,(H,25,27,28)</ns4:inchi_string>
        <oboInOwl:hasRelatedSynonym>troglitazona</oboInOwl:hasRelatedSynonym>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi/3_STAR"/>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



