dermal dendritic cell CD1a-positive dermal dendritic cell CD1a+ dermal DC Reside in the dermis. They are also CD11c-positive, CD40-positive, CD207-negative (langerin), CD209-negative (DC-SIGN), and CD324-negative (E-cadherin). When activated, they are capable of producing CXCL8 (IL-8) and IL-15. Possibly a precursor of Langerhans cells or equivalent of langerin-positive dermal DCs in the mouse. A dermal dendritic cell that is CD1a-positive and CD14-negative.