macromolecule metabolic process obsolete cellular macromolecule metabolic process https://github.com/geneontology/go-ontology/issues/17904 true cellular macromolecule metabolism OBSOLETE. The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. GO:0044260 This term was obsoleted because it is not different from its parent, macromolecule metabolic process ; GO:0043170. biological_process cellular biopolymer metabolic process