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    <!-- http://purl.obolibrary.org/obo/HP_0000520 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0000520">
        <rdfs:label>Proptosis</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012372"/>
        <ns2:gwas_trait rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</ns2:gwas_trait>
        <oboInOwl:hasExactSynonym>Eyeballs bulging out</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>SNOMEDCT_US:18265008</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Ocular proptosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>HP:0000536</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>UMLS:C0015300</oboInOwl:hasDbXref>
        <ns4:IAO_0000115>An eye that is protruding anterior to the plane of the face to a greater extent than is typical.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>Bulging eye</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Protrusio bulbi</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Protruding eyes</oboInOwl:hasExactSynonym>
        <oboInOwl:id>HP:0000520</oboInOwl:id>
        <rdfs:comment>Some sources define &quot;exophthalmos&quot; as a protrusion of the globe greater than 18 mm and &quot;proptosis&quot; as a protusion equal to or less than 18 mm. Others define &quot;exophthalmos&quot; as protusion secondary to endocrine dysfunction and &quot;proptosis&quot; as any non-endocrine-mediated protusion (Source: Wikipedia). This finding should be distinguished frm underdevelopment of the supraorbital ridge or maxilla/zygoma. In proptosis, the globe is anteriorly protuberant to the overall plane of the face.</rdfs:comment>
        <oboInOwl:hasExactSynonym>Exophthalmos</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C1848490</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>HP:0000645</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>HP:0000644</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>Anterior bulging of the globe of eye</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>HP:0007711</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>UMLS:C1862425</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Anterior bulging of the globe</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Prominent globes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>HP:0007870</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>UMLS:C1837760</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Prominent eyes</oboInOwl:hasExactSynonym>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/hp#hposlim_core"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0012372 -->

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        <rdfs:label>Abnormal eye morphology</rdfs:label>
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