Abnormal corpus callosum morphology The corpus callosum, a broad thick band of nerve fibers that connects the right and left cerebral hemispheres, is the largest white matter structure in the brain. This finding can be demonstrated by cerebral magenetic resonance tomography. The corpus callosum structurally consists of 4 major anatomic features including the rostrum, genu, corpus, and splenium. Abnormality of the corpus callosum. HP:0001273 UMLS:C1842581 Abnormal corpus callosum Abnormality of the corpus callosum Corpus callosum abnormality HP:0007323 Abnormal cerebral white matter morphology