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    <!-- http://purl.obolibrary.org/obo/HP_0000818 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0000818">
        <rdfs:label>Abnormality of the endocrine system</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/HP_0004319 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0004319">
        <rdfs:label>Decreased circulating aldosterone concentration</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000818"/>
        <dcterms:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2008-02-25T10:45:00Z</dcterms:date>
        <oboInOwl:hasAlternativeId>HP:0008184</oboInOwl:hasAlternativeId>
        <ns3:IAO_0000115>Abnormally reduced levels of aldosterone.</ns3:IAO_0000115>
        <oboInOwl:hasDbXref>UMLS:C0020595</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Decreased aldosterone</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C1846226</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Decreased aldosterone production</oboInOwl:hasExactSynonym>
        <oboInOwl:id>HP:0004319</oboInOwl:id>
        <rdfs:comment>Aldosterone is a hormone that is produce by the adrenal cortex and that acts on the distal tubules and collecting ducts to favor retention of sodium excretion of potassium, and increased water retention, thereby tending to increase blood pressure. Aldosterone is sometimes called a mineralocorticoid because of its influence on sodium homeostasis.</rdfs:comment>
        <oboInOwl:hasAlternativeId>HP:0008190</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>Mineralocorticoid insufficiency</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>HP:0002924</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>Hypoaldosteronism</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Decreased serum aldosterone</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>HP:0000355</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>Low blood aldosterone level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C0857899</oboInOwl:hasDbXref>
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