Laryngeal cleft Laryngotracheal cleft UMLS:C1840311 Embryologically, the trachea and esophagus share a common lumen until they are separated by the development of the tracheoesophageal septum. Failure of this fusion and incomplete development of the tracheoesophageal septum may lead to congenital abnormalities such as isolatedlaryngeal cleft, tracheoesophageal fistula, and esophageal atresia, depending on the severity of the abnormality. Patients with laryngeal cleft may present with feeding difficulty, chronic cough, stridor, pneumonia or respiratory distress, depending on the size of the cleft. HP:0008751 Laryngotracheoesophageal cleft i SNOMEDCT_US:232461002 Presence of a gap in the posterior laryngotracheal wall with a continuity between the larynx and the esophagus. Abnormal larynx morphology