Abnormality of the liver Abnormality of the immune system Liver abscess 2010-12-20T11:13:14Z true HP:0001400 SNOMEDCT_US:27916005 Liver abscess Purulent hepatic collection A localized, circumscribed collection of purulent material (pus) within the liver parenchyma, typically resulting from a bacterial, parasitic, or fungal infection. Unlike hepatitis, which is often diffuse, an abscess is a focal lesion. UMLS:C0023885 HP:0100523 Unlike hepatitis, which is typically a diffuse inflammatory process, a liver abscess is a focal, localized collection of pus within the liver parenchyma. In addition to being a secondary complication of biliary or intra-abdominal infections, it is a characteristic manifestation of phagocytic defects (e.g., chronic granulomatous disease) and specific innate immune defects, such as NEMO deficiency. Hepatic abscess