nephritis hereditary nephritis hereditary nephritis UMLS:C0027706 MEDGEN:10305 SCTID:399340005 MESH:D009394 MONDO:0005334 familial nephritis nephritis, familial A group of inherited conditions characterized initially by hematuria and slowly progressing to renal insufficiency. The most common form is the Alport syndrome (hereditary nephritis with hearing loss) which is caused by mutations in genes for type IV collagen and defective glomerular basement membrane. inherited kidney disorder