action myoclonus-renal failure syndrome https://github.com/monarch-initiative/mondo/issues/4521 https://www.malacards.org/card/epilepsy_progressive_myoclonic_4_with_or_without_renal_failure_2 https://www.malacards.org/card/progressive_myoclonus_epilepsy_4 OMIM:254900 SCTID:764453009 epilepsy, progressive myoclonic, 4, with or without renal failure AMRF DOID:0111444 Orphanet:163696 UMLS:C0751779 action myoclonus-renal failure syndrome progressive myoclonic epilepsy type 4 Action myoclonus-renal failure syndrome (AMRF) is a rare epilepsy syndrome characterized by progressive myoclonus epilepsy in association with primary glomerular disease. Patients present with neurologic symptoms (including tremor, action myoclonus, tonic-clonic seizures, later ataxia and dysarthria) that may precede, occur simultaneously or be followed by renal manifestations including proteinuria that progresses to nephrotic syndrome and end-stage renal disease. In some patients, sensorimotor peripheral neuropathy, sensorineural hearing loss and dilated cardiomyopathy are associated symptoms. epilepsy, progressive myoclonic 4, with or without renal failure GARD:0017000 MONDO:0009699 MEDGEN:155629 myoclonus-nephropathy syndrome EPM4 progressive myoclonus epilepsy Action myoclonus - renal failure syndrome