synovium cancer hereditary disease synovial sarcoma https://www.malacards.org/card/sarcoma_synovial MESH:D013584 NCIT:C3400 MONDO:0010434 Synovial sarcoma is an aggressive soft tissue sarcoma, occurring most commonly in adolescents and young adults (15 to 40 years), usually localized near the large joints of the extremities but also in the head and neck, mediastinum and viscera (lung, kidney etc), clinically presenting as a deep seated swelling or a painful mass often with an initial indolent course and is characterized by its local invasiveness and a propensity to metastasize. The origin of synovial sarcoma is likely from multipotent mesenchymal cells and not synovium (contrary to its name). NANDO:2200061 ICD9:171.9 SCTID:302851001 HP:0012570 ICDO:9040/3 synovial sarcoma OMIM:300813 synovial sarcoma (disease) UMLS:C0039101 GARD:0007721 MEDGEN:21050 Synovialosarcoma SS EFO:0001376 sarcoma, synovial, malignant synovial sarcoma (disease) ONCOTREE:SYNS MedDRA:10042863 Orphanet:3273 DOID:5485 soft tissue sarcoma obsolete_synovial sarcoma