sick sinus syndrome familial sick sinus syndrome https://www.malacards.org/card/familial_sick_sinus_syndrome true hereditary sick sinus syndrome GARD:0013663 SCTID:233913007 SSS1 MedDRA:10040639 MEDGEN:573766 UMLS:C0340491 Sick sinus syndrome is a rare cardiac rhythm disease, usually of the elderly, characterized by electrocardiographic findings of sinus bradycardia, atrial fibrillation, atrial tachycardia sinus arrest, or sino-atrial block, and that manifest with symptoms like syncope, dizziness, palpitations, fatigue, or even heart failure. It results from malfunction of the cardiac conduction system, probably secondary to degenerative fibrosis of nodal tissue in the elderly or secondary to cardiac disorders in younger patients. sick sinus syndrome 1, autosomal recessive Orphanet:166282 MESH:C563907 familial sinus node dysfunction MONDO:0012061 OMIMPS:608567 icd11.foundation:1495462959 cardiogenetic rhythm disorder obsolete_familial sick sinus syndrome