disease responds to pyridoxal 5'-phosphate pyridoxal phosphate-responsive seizures https://www.epilepsydiagnosis.org/aetiology/metabolic-groupoverview.html#pyridoxine https://www.malacards.org/card/pyridoxamine_5_prime_phosphate_oxidase_deficiency MONDO:0012407 PNPO deficiency PNPO-related neonatal epileptic encephalopathy icd11.foundation:604024463 pyridoxal 5'-phosphate-dependent epilepsy MESH:C566449 pyridox(am)ine 5’-phosphate oxidase deficiency pyridoxine-5'-phosphate oxidase deficiency OMIM:610090 GARD:0010730 UMLS:C1864723 SCTID:724576005 DOID:0111329 pyridoxine 5' phosphate oxidase deficiency MEDGEN:350498 pyridoxamine 5'-phosphate oxidase deficiency pyridoxal phosphate-dependent seizures icd11.foundation:1632334328 PNPOD Orphanet:79096 A very rare neonatal epileptic encephalopathy disorder characterized clinically by onset of severe seizures within hours of birth that are not responsive to anticonvulsants, but are responsive to treatment with pyridoxal phosphate. inborn disorder of pyridoxine metabolism metabolic epilepsy hereditary neurological disease obsolete_pyridoxal phosphate-responsive seizures