disease has location plasma cell type IV hypersensitivity disease leukocyte disorder acquired peripheral neuropathy POEMS syndrome https://www.malacards.org/card/poems_syndrome NORD:1586 Orphanet:2905 Takatsuki syndrome SCTID:79268002 MESH:D016878 POEMS syndrome is a paraneoplastic syndrome characterized by polyradiculoneuropathy (P), organomegaly (O), endocrinopathy (E), clonal plasma cell disorder (M), and skin changes (S). Other features include papilledema, extravascular volume overload, sclerotic bone lesions, thrombocytosis/erythrocytosis, and elevated VEGF levels. NANDO:1200033 POEMS syndrome Crow-Fukase syndrome MONDO:0017364 PEP syndrome polyneuropathy-endocrinopathy-plasma cell dyscrasia syndrome DOID:14039 NCIT:C80303 osteosclerotic myeloma MEDGEN:39276 MedDRA:10053869 icd11.foundation:1555299114 polyneuropathy organomegaly EFO:1001115 GARD:0007411 polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes syndrome UMLS:C0085404 paraneoplastic neurologic syndrome parneoplastic endocrine syndrome paraneoplastic hematological syndrome obsolete_POEMS syndrome