<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/EFO?iri=http://purl.obolibrary.org/obo/MONDO_0019964"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns5="http://purl.obolibrary.org/obo/mondo#"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:skos="http://www.w3.org/2004/02/skos/core#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#curated_content_resource"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000233"/>
    <AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#exactMatch"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0004026 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004026">
        <rdfs:label>disease has location</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/MONDO_0005197 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0005197">
        <rdfs:label>thymus neoplasm</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0019496 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0019496">
        <rdfs:label>neuroendocrine neoplasm</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0019964 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0019964">
        <rdfs:label>thymic neuroendocrine tumor</rdfs:label>
        <equivalentClass>
            <Class>
                <intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/MONDO_0019496"/>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004026"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002370"/>
                    </Restriction>
                </intersectionOf>
            </Class>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005197"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0019496"/>
        <ns4:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/monarch-initiative/mondo/issues/8567</ns4:IAO_0000233>
        <ns5:curated_content_resource rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://www.malacards.org/card/thymic_neuroendocrine_tumor</ns5:curated_content_resource>
        <oboInOwl:hasDbXref>GARD:0019361</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>thymus neuroendocrine tumour</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>Orphanet:97289</oboInOwl:hasDbXref>
        <oboInOwl:id>MONDO:0019964</oboInOwl:id>
        <oboInOwl:hasExactSynonym>thymus NET</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>thymus neuroendocrine neoplasm</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>Thymic endocrine tumor is a rare, malignant, primary thymic neoplasm originating from neuroendocrine cells, presenting as a mass within the anterior mediastinum. Patients typically present with nonspecific symptoms, such as chest pain, cough, shortness of breath, or in some cases, superior vena cava syndrome, although patients could be asymptomatic during the early stages or present with multiple endocrine neoplasia type I. Ectopic production of ACTH and serotonin can lead to Cushing syndrome and carcinoid sydrome, respectively.</ns4:IAO_0000115>
        <oboInOwl:hasDbXref>ONCOTREE:TNET</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>thymus neuroendocrine tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>NCIT:C6430</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>neuroendocrine neoplasm of thymus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>thymus neuroendocrine tumor, well differentiated, low or intermediate grade</oboInOwl:hasExactSynonym>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/NCIT_C6430"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#gard_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#nord_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#ordo_disorder"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#orphanet_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#otar"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#rare"/>
        <skos:exactMatch rdf:resource="http://www.orpha.net/ORDO/Orphanet_97289"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002370 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002370">
        <rdfs:label>thymus</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



