disease has major feature autosomal dominant disease dementia obsolete neuro-ophthalmological disease hereditary dementia autosomal dominant cerebellar ataxia https://github.com/monarch-initiative/mondo/issues/8301 https://github.com/monarch-initiative/mondo/issues/9285 https://github.com/monarch-initiative/mondo/pull/2571/ https://www.malacards.org/card/autosomal_dominant_cerebellar_ataxia Orphanet:99 ADCA cerebellar ataxia, autosomal dominant SCA A clinically and genetically heterogeneous group of neurodegenerative diseases characterized by a slowly progressive ataxia of gait, stance and limbs, dysarthria and/or oculomotor disorder, due to cerebellar degeneration in the absence of coexisting diseases. The degenerative process can be limited to the cerebellum (ADCA type 3) or may additionally involve the retina (ADCA type 2), optic nerve, ponto-medullary systems, basal ganglia, cerebral cortex, spinal tracts or peripheral nerves (ADCA type 1). In ACDA type 4, a cerebellar syndrome is associated with epilepsy. MEDGEN:1684639 spinocerebellar ataxia SCTID:129609000 autosomal dominant spinocerebellar ataxia Autosomal Dominant Hereditary Ataxia Pierre Marie cerebellar ataxia (formerly) MONDO:0020380 UMLS:C4087347 NORD:825 GARD:0004346 ICD9:334.3 OMIMPS:164400 DOID:1441 hereditary cerebellar ataxia obsolete_autosomal dominant cerebellar ataxia