familial cystic renal disease polycystic kidney disease https://github.com/monarch-initiative/mondo/issues/3532 NANDO:1200367 SCTID:82525005 NANDO:2200152 NCIT:C75464 UMLS:C0022680 EFO:0008620 MEDGEN:9639 fibrocystic renal disease OMIMPS:173900 DOID:0080322 A usually autosomal dominant and less frequently autosomal recessive genetic disorder characterized by the presence of numerous cysts in the kidneys leading to end-stage renal failure. The autosomal dominant trait is associated with abnormalities on the short arm of chromosome 16. Symptoms in patients with the autosomal dominant trait usually appear at middle age and include abdominal pain, hematuria, and high blood pressure. Patients may develop brain aneurysms and liver cysts. Patients with the autosomal recessive trait present with progressive renal failure early in life and symptoms resulting from hepatic fibrosis. The autosomal recessive trait is associated with abnormalities of chromosome 6. Polycystic kidney disease may also result as a side effect in patients on renal dialysis. MONDO:0020642 MESH:D007690 polycystic kidney disease PKD - polycystic kidney disease obsolete_Polycystic Kidney Disease