hereditary peripheral neuropathy PRPS1 deficiency disorder 2018-10-10T21:18:33Z https://github.com/monarch-initiative/mondo/issues/7700 GARD:0026031 MONDO:0100061 PRPS1 deficiency disorder PRPS1-related CMTX5/Arts syndrome/XLNSHL A peripheral neuropathy that is characterized by variants in PRPS1, which causes decreased or impaired function of the PRPS1 enzyme, and presents as a range of peripheral neuropathies that can include features of Charcot-Marie Tooth syndrome, Arts syndrome, or nonsyndromic hearing loss.