hereditary disease developmental defect during embryogenesis TP63-related ectodermal dysplasia spectrum with limb and orofacial malformations MONDO:1040001 Any developmental defect during embryogenesis in which the cause of the disease is a mutation in the TP63 gene. This disease is characterized by variable ectodermal dysplasia, limb defects, and orofacial clefting. https://github.com/monarch-initiative/mondo/issues/8292 GARD:0028141