shaker-related voltage-gated potassium channel alpha subunit voltage-gated potassium channel subunit KCNA10 voltage-gated potassium channel subunit Kv1.8 protein Category=gene. PR:000000809 A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA10 gene or a 1:1 ortholog thereof. It is a subunit of the Kv1.8 channel is a delayed rectifier channel that may be involved in regulating the tone of renal vascular smooth muscle and may also participate in the cardiac action potential. It is regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. It can coassemble with other Kv1 subunits. IUPHARobj:545 KCNA10