part_of part of part of Homo sapiens zone of skin anatomical structure skin epidermis hair follicle https://upload.wikimedia.org/wikipedia/commons/4/4d/Hair_follicle-en.svg EFO:0002464 UMLS:C0221971 MA:0000154 EV:0100156 A tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open[GO]. UBERON:0002073 GAID:934 folliculus pili FMA:70660 Wikipedia:Hair_follicle SCTID:280830006 NCIT:C13317 BTO:0000554 The earliest reliable record of hair is found in a fossil of the Paleocene period, in which the structure of hair cuticles is preserved. Its appearance suggests that the complicated structure of the hair follicle, closely similar to that of present-day mammals, had already appeared at this time.[well established][VHOG] MESH:D018859 EMAPA:29741 VHOG:0001268 Development notes:Formation largely takes place during fetal and perinatal skin development. However, after skin wounding de novo hair follicle formation may also occur in adult mouse and rabbit skin[DOI:10.1016/j.cub.2008.12.005]. EMAPA:18771 CALOHA:TS-0432 pilosebaceous unit