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    <!-- http://www.ebi.ac.uk/efo/EFO_0000270 -->

    <Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0000270">
        <rdfs:label>obsolete_asthma</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
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        <oboInOwl:hasExactSynonym>BHR - Bronchial hyperreactivity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>MedDRA:10003553</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Pneumopathy due to inhalation of other dust</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>OMIM:608584</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>chronic obstructive asthma with acute exacerbation</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Asthmatic</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bronchial Hyperreactivities</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Exercise induced asthma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>NCIt:C28397</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Bronchial hypersensitivity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Asthma, unspecified</oboInOwl:hasExactSynonym>
        <ns5:reason_for_obsolescence>Replaced with Mondo term
see https://github.com/ebispot/efo/issues/1381</ns5:reason_for_obsolescence>
        <oboInOwl:hasExactSynonym>Pneumopathy due to inhalation of other dust NOS</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>chronic obstructive asthma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>OMIM:611064</oboInOwl:hasDbXref>
        <ns2:IAO_0000117>James Malone</ns2:IAO_0000117>
        <oboInOwl:hasExactSynonym>Asthma NOS (disorder)</oboInOwl:hasExactSynonym>
        <ns5:obsoleted_in_version>3.38.0</ns5:obsoleted_in_version>
        <oboInOwl:hasExactSynonym>ASTHMA NOS W (AC) EXAC</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Pneumonopathy due to inhalation of other dust</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Airway hyperreactivity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bronchial hyperresponsiveness</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Pneumopathy due to inhalation of other dust NOS (disorder)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Asthma NOS</oboInOwl:hasExactSynonym>
        <ns2:IAO_0000115>Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.</ns2:IAO_0000115>
        <oboInOwl:hasExactSynonym>DUST PNEUMONOPATHY NEC</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>ICD10:J45</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Asthma unspecified</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Pneumopathy due to inhalation of other dust (disorder)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Asthma, unspecified type, without mention of status asthmaticus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Hyperreactive airways disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>OMIM:611960</oboInOwl:hasDbXref>
        <ns2:IAO_0000115>A chronic respiratory disease manifested as difficulty breathing due to the narrowing of bronchial passageways.</ns2:IAO_0000115>
        <oboInOwl:hasExactSynonym>Other forms of asthma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>ICD9:493</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT:195967001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>OMIM:607277</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Asthma, Bronchial</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Asthmas</oboInOwl:hasExactSynonym>
        <ns2:IAO_0000117>Tomasz Adamusiak</ns2:IAO_0000117>
        <oboInOwl:hasExactSynonym>Bronchial hyperreactivity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Asthma unspecified (disorder)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Hyperreactivity, Bronchial</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>OMIM:600807</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MedDRA:10003561</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MedDRA:10003562</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MedDRA:10003563</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DOID:2841</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Asthma (disorder)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Hyperreactive airway disease</oboInOwl:hasExactSynonym>
        <ns2:IAO_0000115>A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).</ns2:IAO_0000115>
        <ns2:IAO_0100001>http://purl.obolibrary.org/obo/MONDO_0004979</ns2:IAO_0100001>
        <oboInOwl:hasExactSynonym>Bronchial asthma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Asthma, unspecified type, with acute exacerbation</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Hyperreactivities, Bronchial</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>chronic obstructive asthma with status asthmaticus</oboInOwl:hasExactSynonym>
        <ns2:IAO_0000115>A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, excercise, stress, reflux disease, medications, foods and emotional anxiety.</ns2:IAO_0000115>
        <oboInOwl:hasExactSynonym>BA</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Exercise-induced asthma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>MESH:D001249</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Exercise-induced asthma (disorder)</oboInOwl:hasExactSynonym>
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