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    <!-- http://www.ebi.ac.uk/efo/EFO_0000335 -->

    <Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0000335">
        <rdfs:label>obsolete_chromophobe renal cell carcinoma</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://rarediseases.info.nih.gov/diseases/6064/chromophobe-renal-cell-carcinoma</rdfs:seeAlso>
        <deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</deprecated>
        <ns4:IAO_0000115>Chromophobe renal cell carcinoma is a rare subtype of renal cell carcinoma, originating from the intercalating cells of the collecting ducts and macroscopically manifesting as a well-circumscribed, highly lobulated, solid tumor that is usually diagnosed at an early stage. It is frequently asymptomatic, or may present with nonspecific symptoms, such as weight loss, fever or fatigue. The classic presentation observed in renal tumors (hematuria, flank pain and palpable mass) is occasionally observed and usually indicates an advanced stage of the disease. It is most frequently sporadic however, several familial cases, associated with Birt-Hogg DubC) syndrome, have been described.</ns4:IAO_0000115>
        <oboInOwl:hasDbXref>UMLS:C1266042</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000335</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DOID:4471</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>chromophobe cell carcinoma of kidney</oboInOwl:hasExactSynonym>
        <ns4:IAO_0100001>http://purl.obolibrary.org/obo/MONDO_0017885</ns4:IAO_0100001>
        <oboInOwl:hasExactSynonym>renal cell carcinoma, chromophobe cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>GARD:0006064</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>CRCC</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>chromophobe renal cell cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>ICD10:C64</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>ChRCC</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>SCTID:733471003</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>chromophobe carcinoma of the kidney</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>kidney chromophobe</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>chromophobe renal cell adenocarcinoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C3887514</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>chromophobe carcinoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>ONCOTREE:CHRCC</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>CHRCC</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Orphanet:319303</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:8317/3</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>renal cell carcinoma, chromophobe type</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>NCIT:C4146</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>chromophobe adenocarcinoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>chromophobe cell carcinoma of the kidney</oboInOwl:hasExactSynonym>
        <ns5:reason_for_obsolescence>Replaced by Mondo term MONDO_0017885, with which this term was previously merged. Use: http://purl.obolibrary.org/obo/MONDO_0017885</ns5:reason_for_obsolescence>
        <oboInOwl:hasDbXref>ICDO:8270/3</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>chromophobe renal cell carcinoma</oboInOwl:hasExactSynonym>
        <ns5:obsoleted_in_version>3.88.0</ns5:obsoleted_in_version>
        <oboInOwl:hasExactSynonym>chromophobe carcinoma of kidney</oboInOwl:hasExactSynonym>
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