obsolete_chronic myelogenous leukemia true true http://purl.obolibrary.org/obo/MONDO_0011996 chronic myelogenous leukemia chronic myelocytic leukemia COHD:134603 3.88.0 DOID:8552 leukemia, chronic myelogenous ICDO:9863/3 ICD9:205.1 chronic granulocytic leukemia chronic myelogenous leukemias chronic myelogenous leukemia, BCR-ABL1 positive A chronic myeloproliferative neoplasm characterized by the expression of the BCR-ABL1 fusion gene. It presents with neutrophilic leukocytosis. It can appear at any age, but it mostly affects middle aged and older individuals. Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly. If untreated, it follows a biphasic or triphasic natural course; an initial indolent chronic phase which is followed by an accelerated phase, a blast phase, or both. Allogeneic stem cell transplantation and tyrosine kinase inhibitors delay disease progression and prolong overall survival. chronic myeloid leukemia Orphanet:521 GARD:0006105 NCIT:C3174 leukemia, chronic myeloid, atypical ONCOTREE:CML BCR-ABL Positive chronic myelogenous leukemia MedDRA:10009013 leukemia, chronic myeloid EFO:0000339 chronic myelogenous leukemia (CML) ICDO:9875/3 UMLS:C0023473 chronic myelogenous leukemia, BCR-ABL1 Positive ICD10:C92.1 CML myeloid leukemia, chronic KEGG:05220 hematopoeitic - chronic myelocytic leukemia (CML) OMIM:608232 CML - chronic myelogenous leukemia Replaced by Mondo term MONDO_0011996, with which this term was previously merged. Use: http://purl.obolibrary.org/obo/MONDO_0011996