obsolete_classical Hodgkin's lymphoma true http://purl.obolibrary.org/obo/MONDO_0004952 true 1.5 C7164 James Malone A monoclonal B-cell lymphoproliferation in the vast majority of cases. It is characterized by a bimodal age distribution (15-30 years of life and late life) and is often associated with EBV infection. In less than 5% of cases it is a monoclonal proliferation of T-lymphocytes. Morphologically, it is characterized by the presence of Reed-Sternberg cells and mononuclear Hodgkin cells. The Reed-Sternberg and mononuclear Hodgkin cells are CD30 positive in nearly all cases and CD15 positive in the majority of cases. Duplicate with Hodgkin's lymphoma (EFO_0000183)