obsolete_colon adenocarcinoma true 2.6.1 DOID:234 true Use http://www.ebi.ac.uk/efo/EFO_0000365 colorectal adenocarcinoma NCIt:C4349 James Malone An adenocarcinoma arising from the colon. It is more frequently seen in populations with a Western type diet and in patients with a history of chronic inflammatory bowel disease. Signs and symptoms include intestinal bleeding, anemia, and change in bowel habits. According to the degree of cellular differentiation, colonic adenocarcinomas are divided into well differentiated, moderately, and poorly differentiated. Morphologic variants include the mucinous adenocarcinoma and signet-ring adenocarcinoma. Lymphatic or hematogenous spread can occur early in the process and lead to systemic disease. http://purl.obolibrary.org/obo/MONDO_0005008